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- EC HPLC column (analytical), NUCLEODUR C18 Gravity, 3 µm, 100x4.6 mm
This high density C18 phase based on high purity NUCLEODUR silica gel with its endcapping suppresses any unwanted polar interactions between the silica surface and the sample, which makes “Gravity” particularly suitable for the separation of basic and other ionizable analytes. Due to the enhanced pH stability, LC/MS suitability and superior base deactivation (BDS) it is a perfect choice for method development and valuable for RP applications.
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			Brand NUCLEODUR Pore size 110 Å Specific surface according to BET 340 m²/g Base material NUCLEODUR - high purity silica Particle type Fully porous particles (FPP) Particle shape Spherical Mode Reversed phase (RP) USP listing L1 Endcapped Yes pH stability 1.0–11.0 Scope of delivery 1x analytical HPLC column, instruction leaflet, certificate of analysis Recommended application(s) RP applications HPLC Recommended application(s) Reversed phase Recommended application(s) Pharmaceuticals Recommended application(s) Analgesics Recommended application(s) Antiinflammatory drugs Recommended application(s) Antidepressants Recommended application(s) Herbicides Recommended application(s) Phytopharmaceuticals Recommended application(s) Immunosuppressants Recommended application(s) Applications at pH extremes (1-11) Recommended application(s) Ideal for method development Temperature stability (max) 60 °C Tmax (phosphate buffer) 40 °C Pressure stability (max) 600 bar Method HPLC, analytical Hardware Stainless steel Type EC HPLC column (analytical) Phase NUCLEODUR C18 Gravity Particle size 3 µm Pore volume 0.9 mL/g Carbon content 18.0 % Surface chemistry High density octadecyl (C18, ODS) modification Surface chemistry Base deactivated (BDS) Eluent in HPLC column Acetonitrile – water Column inner diameter 4.6 mm Column length 100 mm Column volume 1.65 mL 
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