Solid phase extraction (SPE, Automated)

Automated SPE – CHROMABOND for reproducible results

Performing Solid Phase Extraction (SPE) manually can be time consuming and nerve-racking, especially when recovery and reproducibility are lacking due to sample variability. If SPE can be reliably automated, it becomes a much more efficient and reproducible process for high-throughput applications.

MPS and ASPEC

MACHEREY‑NAGEL produce special SPE columns already equipped with special caps and needles (cannulas) to be used in the SPE unit of the Gerstel MultiPurposeSampler (MPS), available in 1, 3 and 6 mL and columns for Gilson ASPEC systems are ready-to-use assembled with caps.

On-line SPE

MN also offers different on-line column configurations designed to fit your on-line SPE analysis needs and filled with a choice of different particle sizes and modifications:
Ready-to-use columns for online-SPE made of stainless steel in standard dimensions 20 x 2 mm and 20 x 4 mm packed with for example CHROMABOND HR-Xpert phases (15 µm particles) or with NUCLEODUR C18 ec, C8 ec, CN (20 µm particles).
On-line SPE is a powerful method in automated sample preparation where the SPE hardware is technically integrated into a HPLC system. Crude samples are placed in an autosampler and processed fully automatic prior to injection into a GC (MS) or LC (MS) system. These products are only on request available and do not belong to the webshop product portfolio.

Good to know

  • MACHEREY-NAGEL offers various solutions for automated solid phase extraction.
  • SPE can be automated for high-throughput applications.
  • 96-well plates are available for solid phase extraction (SPE) and for filtration.