A syringe termination determines how a syringe is connected to a needle. Hamilton manufactures syringes with 17 distinct terminations, and among the most common are "cemented needle" (N), "removable needle" (RN) and "PTFE Luer Lock" (TLL). To learn more about syringe terminations, read the article below with images and descriptions of each termination.
N, Cemented Needle
For low volume syringes the needles are cemented into the glass syringe barrel at a point corresponding to the zero graduation mark. With this termination, dead volume is limited to the internal volume of the needle. Not autoclavable. Needle gauge is determined by the syringe volume and are not user-selectable.
SN, Special Cemented Needle
For low volume syringes the special needle terminations are the same as the Cemented Needle terminations except they allow for a variety of user-defined gauges, lengths and point styles to be attached.
LTN, Luer Tip Cemented Needle
For mid volume syringes the needles are cemented into the glass syringe barrel at a point corresponding to the zero graduation mark. With this termination, dead volume is limited to the internal volume of the needle. Not autoclavable. Needle gauge is determined by the syringe volume and are not user-selectable.
LTN, Luer Tip Special Cemented Needle
For mid volume syringes the special needle terminations are the same as the Luer Tip Cemented Needle terminations except they allow for a variety of user-defined gauges, lengths and point styles to be attached.
LT, Luer Tip
The needles are removable and fit over a ground glass hub which is tapered in the shape of a male luer. The LT termination will accept most hypodermic needles but was designed specifically for use with Hamilton Kel-F Hub needles. This termination increases the dead volume in the syringe, which may not be appropriate for some applications. Autoclavable when disassembled.
RN, Removable Needle
This Hamilton-specific design allows for the needles to be removed or replaced with a Small or Large RN Hub needle. The design allows the needles to seat precisely at the zero graduation mark of the syringe. Users can select the needle gauge, length and point style to optimize the syringe for custom applications. Additionally, this termination allows for a removable needle without increasing the dead volume of the syringe and is ideal when there is a risk of the needle clogging. Autoclavable when disassembled. Repeated autoclaving may shorten the syringe life.
KH, Knurled Hub
The knurled hub is used exclusively on 7000 Series syringes. There is a fine wire extension of the plunger which extends all the way to the tip of the needle, making it a zero dead volume syringe. While the needle is technically removable, it is not recommended to remove the needle as it is extremely difficult to rethread the wire back through the needle without damaging it. Additionally, all sample aspirated into a 7000 series syringe is retained within the needle, so the gauge cannot be swapped as this would affect the volume. The hub handles up to 6000 psig maximum injection pressure. The needle is removable but with a limited number of gauges available because the plunger is fitted inside the needle. Autoclavable when disassembled. Repeated autoclaving will shorten syringe life.
FN, Fixed Needle
This termination is found on CTC chromatography syringes. The unique design features a direct attachment of the needle to the barrel and eliminates contact between the sample solvent and the adhesive reducing carry-over.
TLL, PTFE® Luer Lock
This termination has a PTFE, male Luer taper with nickel-plated brass locking hub for use with Kel-F Hub needles, Metal Hub needles and universal connectors. Also, the TLL is used with Hamilton Diluters/Dispensers, OEM applications and manual operations. Autoclavable when disassembled, except on 25 mL and greater syringes. Repeated autoclaving will shorten syringe life.
BFP, Bubble Free Prime
The 5/16"-28 threaded hub is commonly used with the Microlab 600 syringe pumps. The Bubble Free Prime Syringes feature a conical plunger tip which extends through the threaded termination and into the valve. This unique design expels the air from the syringe and valve, decreasing the number of priming cycles required.
The SampleLock incorporates an On/Off syringe valve with a Removable Needle hub. This termination is used for headspace, environmental sample collection and storage, pre-pressurization of gaseous samples for GC analysis, and sample spiking. Not autoclavable. Compatible with Large RN Hub needles.
The ChemSeal termination features a ¼-28 UNF male fitting. This syringe is used in low volume applications where system dead volume needs to be minimized. These syringes can be screwed directly into Hamilton HV, HVP, HVX valves.
CA, Carbon Analyzer
This syringe is used for water analysis with total organic carbon (TOC) analyzers. The termination is designed to minimize the chance of organic carbon contamination from the needle connection.
DX, Diluter with Stop
This is a PTFE Luer Lock Male fitting with an M6 female side port. These syringes attach to instrumentation such as the Microlab 500 series diluters and dispensers.
DAD, Diluter AccuDil
These syringes have an axial fine thread M8 x 0.75 and an M6 female side port. These syringes attach to instrumentation such as the Microlab 1000 series diluters and dispensers.
These syringes have an axial fine thread M8 x 0.75. These syringes attach to instrumentation such as the Microlab 1000 series Diluters/Dispensers.
This termination accepts 5/8" I.D. flexible tubing. These syringes are used for air sampling, preparing gas standards, calibrating reservoirs and pneumographs.