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- HPTLC/TLC glass plates, silica layer with chiral selector, CHIRALPLATE, 5x20 cm
CHIRALPLATE - Special layer for TLC enantiomer separation. Separation based on ligand exchange, i. e. formation of ternary mixed-ligand complexes with Cu(II) ions. Differences in the stability of the diastereomeric complexes cause chromatographic separation. Available as glass plates with fluorescent indicator. A review on the application of CHIRALPLATE has been given by K. Günther [J. Chromatogr. 448 (1988) 11–30].
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Particle type
Fully porous particles (FPP)
pH stability
2.0–8.0
Particle shape
Irregular
Pore size
Not available or not applicable
Particle size
Not available or not applicable
Recommended application(s)
Amino acids
Recommended application(s)
Enantiomers
Recommended application(s)
α-hydroxycarboxylic acids
Pore volume
Not available or not applicable
Temperature stability
High
Plate size
5x20 cm
Layer thickness
0.25 mm
Support material / backing
Glass
Binder
Yes
Layer hardness
Standard, soft
UV indicator
Yes
Method
Thin layer chromatography (HPTLC/TLC)
Mode
Reversed phase (RP) with ligand exchange
Recommended application(s)
N-methylamino acids
Recommended application(s)
N-formylamino acids
Recommended application(s)
α-alkylamino acids
Recommended application(s)
Thiazolidine derivatives
Recommended application(s)
Dipeptides
Recommended application(s)
Lactones
Phase
CHIRALPLATE
Base material
Glass plates coated with impregnated silica gel
Surface chemistry
Silica gel impregnated with Cu(II) ions and a chiral selector (proline derivative)
Scope of delivery
50x TLC glass plates (5x20 cm)
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