MSHFBA is used either alone or in combination with a catalyst (TMCS, TSIM) or another silylation reagent with or without solvent. The by-product N-methylheptafluorobutyric amide has a lower retention time than the silylating reagent. Especially useful for flame ionisation detection due to the large ratio of fluorine to silicon of 7:1, since degradation of the excess of MSHFBA does not produce SiOâ‚‚ but volatile, non-corrosive silicon compounds. These products contain harmful substances which must be specially labeled as hazardous. For detailed information please see SDS.
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Derivatization type
Silylation
Method
Gas chromatography (GC), derivatization
Recommended application(s)
Derivatization
Recommended application(s)
Alcohols
Recommended application(s)
Carboxylic acids
Recommended application(s)
Phenols
Composition
N-methyl-N-trimethylsilyl-heptafluorobutyramide (MSHFBA)
Recommended application(s)
Primary and secondary amines
Recommended application(s)
Amino acids
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