EC HPLC column (analytical), NUCLEODEX BETA-OH, 5 µm, 200x4 mm

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SKU: 720124.4

EC HPLC column (analytical), NUCLEODEX BETA-OH, 5 µm, 200x4 mm

Cyclodextrin-modified silica phases for HPLC enantiomer separation. Separation based on hydrogen bonds and dipole interactions between functional groups of the analyte and hydroxyl groups of the cyclodextrin. For compounds, which require free hydroxyl groups for enantioselective interactions.
  • Recommended application(s)

    HPLC

    Particle type

    Fully porous particles (FPP)

    Particle shape

    Spherical

    Endcapped

    No

    Mode

    Special application or diverse

    Pore size

    100 Å

    Particle size

    5 µm

    Scope of delivery

    1x analytical HPLC column, instruction leaflet, certificate of analysis

    Method

    HPLC, analytical

    Hardware

    Stainless steel

    Type

    EC HPLC column (analytical)

    Column inner diameter

    4 mm

    Column volume

    2.5 mL

    Carbon content

    Not available or proprietary

    Pressure stability (max)

    400 bar

    Pore volume

    1 mL/g

    Specific surface according to BET

    350 m²/g

    Base material

    NUCLEOSIL - the standard silica

    Brand

    NUCLEODEX

    Recommended application(s)

    Chiral, enantiomers

    Recommended application(s)

    Enantiomers

    Recommended application(s)

    Chlorthalidone

    Recommended application(s)

    Compounds, which require free hydroxyl groups for enantioselective interactions

    Temperature stability (max)

    50 °C

    Column length

    200 mm

    pH stability

    3.0–8.0

    USP listing

    L45

    Phase

    NUCLEODEX BETA-OH

    Surface chemistry

    β-cyclodextrin (chiral selector) modification

    Eluent in HPLC column

    CH₃OH (methanol) – 0.1 % TEAA (triethylammonium acetate), pH 4 (55/45, v/v)

  • Macherey Nagel - Chromatography Catalogue