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- EC UHPLC column (analytical), NUCLEODUR C8 Gravity, 1.8 µm, 100x4.6 mm
This high density C8 phase based on high purity NUCLEODUR silica gel with its endcapping suppresses any unwanted polar interactions between the silica surface and the sample, which makes “Gravity” particularly suitable for the separation of basic and other ionizable analytes. Due to the enhanced pH stability, LC/MS suitability and superior base deactivation (BDS) it is a perfect choice for method development and valuable for RP applications.
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Brand
NUCLEODUR
Pore size
110 Å
Specific surface according to BET
340 m²/g
Base material
NUCLEODUR - high purity silica
Particle type
Fully porous particles (FPP)
Particle shape
Spherical
Mode
Reversed phase (RP)
Endcapped
Yes
pH stability
1.0–11.0
Recommended application(s)
Pharmaceuticals
Recommended application(s)
Analgesics
Recommended application(s)
Antiinflammatory drugs
Recommended application(s)
Antidepressants
Recommended application(s)
Herbicides
Recommended application(s)
Phytopharmaceuticals
Recommended application(s)
Immunosuppressants
Recommended application(s)
Applications at pH extremes (1-11)
Recommended application(s)
Ideal for method development
Temperature stability (max)
60 °C
Tmax (phosphate buffer)
40 °C
Pressure stability (max)
600 bar
Hardware
Stainless steel
Pore volume
0.9 mL/g
Surface chemistry
Base deactivated (BDS)
Eluent in HPLC column
Acetonitrile – water
Column inner diameter
4.6 mm
Column length
100 mm
Column volume
1.65 mL
Recommended application(s)
Similar to NUCLEODUR C18 Gravity
Recommended application(s)
Decreased retention of non-polar compounds
Recommended application(s)
Suitable for LC-MS
USP listing
L7
Phase
NUCLEODUR C8 Gravity
Carbon content
11.0 %
Surface chemistry
High density monomeric octyl (C8, MOS) modification
Recommended application(s)
RP applications UHPLC
Particle size
1.8 µm
Scope of delivery
1x analytical HPLC/UHPLC column, instruction leaflet, certificate of analysis
Method
HPLC/UHPLC, analytical
Type
EC UHPLC column (analytical)
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