Unlock the power of HPLC columns from Macherey-Nagel with ESSLAB's expertise

At ESSLAB, we don't just supply products, we deliver analytical solutions backed by technical expertise and unwavering support.
The selection of the right column is a critical factor in ensuring accurate and reproducible results. The final packing of the column is paramount, especially when aiming for excellent batch-to-batch reproducibility. This becomes even more vital when attempting to reproduce methods over time, using replacement columns.

The significance of column packing: Why it matters
The success of any chromatographic analysis depends on the precision with which the final column is packed. Achieving excellence in this manufacturing process directly translates into reproducibility —crucial for researchers and analysts striving to replicate their methods weeks, months, or even years later with new replacement columns. Selection by matching up column physical specifications and chemistries might seem straightforward, but the key issue is how consistently these specifications are met during the manufacturing and packing processes.
Macherey-Nagel's commitment to quality: A solid foundation
Macherey-Nagel, a renowned name in chromatography, has set the standard for column manufacturing. Their commitment to stringent quality control and manufacturing processes ensures that each column batch meets the same high standards. This commitment extends to controlled column packing techniques, which play a key role in minimising variability - ensuring consistency in performance. The use of high-purity silica minimizes interference with analyte interactions, ensuring that retention times remain reproducible across different runs. Analysts can rely on the consistency of results, thanks to the excellent batch-to-batch reproducibility.
Peer-reviewed publications:
Columns that are supported by peer-reviewed publications add an additional layer of credibility to their performance claims. Published data provides independent verification of columns’ capabilities, and can serve as an invaluable reference for scientists developing new analytical methods. Publications also demonstrate that columns have been tested and validated by the scientific community.

Method development and optimization:
Reliable columns from reputable manufacturers simplify method development and optimise analytical processes. When working with well-characterized columns, scientists can focus on optimising other parameters of the chromatographic method, such as mobile phase composition, flow rates, and detection conditions, without concerns about column variability.
Regulatory compliance:
In highly regulated industries such as environmental and biopharmaceutical labs, using columns and other essential consumables from manufacturers with established, documented quality systems facilitates regulatory compliance.
ESSLAB’s role: expert guidance in column selection
In the pursuit of chromatographic analytical performance, the analyst is not alone. ESSLAB is a trusted ally, offering sound advice on the selection of columns that align with the analytical demands of each unique application.

Why ESSLAB stands out:

1. Technical expertise:
• ESSLAB's team comprises experienced professionals with a wealth of technical knowledge in chromatography. Analysts benefit from their in-depth knowledge, receiving guidance on selecting columns tailored to their specific needs.
2. Extensive product range:
• ESSLAB’s website proudly hosts an extensive and diverse range of high quality products, including: Macherey-Nagel columns: the high-purity NUCLEODUR, the reliable NUCLEOSIL, and the cutting-edge NUCLEOSHELL. This wide product range allows analysts to choose columns that perfectly suit their analytical requirements.
3. Precision in column matching:
• The team at ESSLAB understands the intricacies of column matching. They ensure that analysts not only match physical specifications and chemistries but also consider the specific demands of their analytical methods, resulting in reliable and reproducible chromatographic performance.
4. Supply chain excellence:
• ESSLAB's robust supply chain ensures that all customers receive high quality products consistently and promptly. This reliability in the supply chain translates into confidence in the continuity of analysis.

How to access ESSLAB's expertise: calling all analysts

Ready to elevate your chromatographic experience with expert guidance in column selection?

ESSLAB's expert team know their stuff but won't overwhelm you with jargon. They'll listen carefully to your requirements and explain the options in a way that makes sense to you.
Whether you're establishing a new method or replacing a column for ongoing analyses, ESSLAB is your trusted partner in achieving sound and reproducible results.
The choices made today impact the results of tomorrow. With ESSLAB by your side, navigate the complexities of column selection with confidence, precision, and the assurance of chromatographic excellence.

Contact us today by live chat, email or phone – essential technical and pricing information can be found here:


Leave a comment

Please note: comments must be approved before they are published.